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Adenosine diphosphate ( ADP) receptor inhibitors are a drug class of antiplatelet agents, used in the treatment of acute coronary syndrome (ACS) or in preventive treatment for patients who are in risk of thromboembolism, myocardial infarction or a stroke. These drugs antagonize the P2Y 12 platelet receptors and therefore prevent the binding of ...
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ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase. In enzymology, a ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase ( EC 3.2.2.6) is a bifunctional enzyme that catalyzes the chemical reaction. The 3 substrates of this enzyme are NAD + and H 2 O, whereas its two products are ADP-ribose and nicotinamide. The reaction proceeds through cyclic ADP ...
In enzymology, a glucose-1-phosphate adenylyltransferase ( EC 2.7.7.27) is an enzyme that catalyzes the chemical reaction. Thus, the two substrates of this enzyme are ATP and alpha-D- glucose 1-phosphate, whereas its two products are diphosphate and ADP-glucose . This enzyme belongs to the family of transferases, specifically those transferring ...
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Adenosine diphosphate ribose (ADPR) is an ester molecule formed into chains by the enzyme poly ADP ribose polymerase. ADPR is created from cyclic ADP-ribose (cADPR) by the CD38 enzyme using nicotinamide adenine dinucleotide (NAD +) as a cofactor. ADPR binds to and activates the TRPM2 ion channel. ADPR is the most potent agonist of the TRPM2 ...
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Adenosine diphosphate (ADP), also known as adenosine pyrophosphate (APP), is an important organic compound in metabolism and is essential to the flow of energy in living cells. ADP consists of three important structural components: a sugar backbone attached to adenine and two phosphate groups bonded to the 5 carbon atom of ribose .