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Human leukocyte antigen. The human leukocyte antigen ( HLA) system or complex of genes on chromosome 6 in humans which encode cell-surface proteins responsible for regulation of the immune system. [1] The HLA system is also known as the human version of the major histocompatibility complex (MHC) found in many animals. [2]
Alpha toxin from S. aureus ( PDB: 7ahl ). Alpha-toxin, also known as alpha-hemolysin (Hla), is the major cytotoxic agent released by bacterium Staphylococcus aureus and the first identified member of the pore forming beta-barrel toxin family. [1] This toxin consists mostly of beta-sheets (68%) with only about 10% alpha-helices.
HLA-NET is a network targeted to the study of Human leukocyte antigen (HLA) from a populational point of view. The network was initiated by COST Action BM0803 [1] in January 2009. Currently HLA-NET activities are being coordinated by a subcommittee of the scientific committee of the European Federation for Immunogenetics .
The HLA Informatics Group ( HIG) is a research group led by Professor Steven Marsh at the Anthony Nolan Research Institute that develops, runs and maintains the IMGT ( immunogenetics )/HLA ( Human leukocyte antigen) Database and the IPD (immuno polymorphism database). The IMGT/HLA database originated as part of IMGT and was merged with IPD in ...
Human leukocyte antigens (HLA) began as a list of antigens identified as a result of transplant rejection. The antigens were initially identified by categorizing and performing massive statistical analyses on interactions between blood types. [1] This process is based upon the principle of serotypes.
HLA-A23. HLA-A23 (A23) is a human leukocyte antigen serotype within HLA-A serotype group. The serotype is determined by the antibody recognition of α 23 subset of HLA-A α-chains. For A23, the alpha, "A", chain are encoded by the HLA-A *23 allele group and the β-chain are encoded by B2M locus. [1] This group currently is dominated by A*2301.
HLA-A is a group of human leukocyte antigens (HLA) that are encoded by the HLA-A locus, which is located at human chromosome 6p21.3. HLA is a major histocompatibility complex (MHC) antigen specific to humans. HLA-A is one of three major types of human MHC class I transmembrane proteins. The others are HLA-B and HLA-C.
HLA-A3. HLA-A3 (A3) is a human leukocyte antigen serotype within HLA-A serotype group. The serotype is determined by the antibody recognition of α 3 subset of HLA-A α-chains. For A3, the alpha, "A", chain are encoded by the HLA-A *03 allele group and the β-chain are encoded by B2M locus. [1] This group currently is dominated by A*03:01.
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