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KEGG. D12607. A respiratory syncytial virus vaccine, or RSV vaccine, is a vaccine that protects against respiratory syncytial virus. [11] RSV affects an estimated 64 million people and causes 160,000 deaths worldwide each year. [14] The RSV vaccines Arexvy ( GSK ), [3] and Abrysvo ( Pfizer ), [8] are approved for medical use in the United States.
Graphic from the World Health Organization describing the main ingredients typically in vaccines. A vaccine dose contains many ingredients (stabilizers, adjuvants, residual inactivating ingredients, residual cell culture materials, residual antibiotics and preservatives) very little of which is the active ingredient, the immunogen. A single ...
RSV leads to 58,000 to 80,000 hospitalizations among children under age 5, and 60,000 to 160,000 hospitalizations among adults age 65 and older each year, according to the CDC.
The CDC lists the following as possible side effects of the RSV vaccine: Pain, redness, and swelling where the shot is given. Fatigue. Fever. Headache. Nausea. Diarrhea. Muscle or joint pain ...
Respiratory syncytial virus ( RSV ), [a] also called human respiratory syncytial virus ( hRSV) and human orthopneumovirus, is a contagious virus that causes infections of the respiratory tract. It is a negative-sense, single-stranded RNA virus. [2] Its name is derived from the large cells known as syncytia that form when infected cells fuse.
Early symptoms of RSV in children can include a runny nose, reduced appetite and a cough, which may progress to wheezing. Infants less than 6 months old will almost always show symptoms that can ...
Palivizumab is a humanized monoclonal antibody (IgG) directed against an epitope in the A antigenic site of the F protein of RSV. In two phase III clinical trials in the pediatric population, palivizumab reduced the risk of hospitalization due to RSV infection by 55% and 45%. [5]
Nirsevimab. Nirsevimab, sold under the brand name Beyfortus, is a human recombinant monoclonal antibody with activity against respiratory syncytial virus (RSV). [10] [11] It is a respiratory syncytial virus (RSV) F protein‑directed fusion inhibitor [6] that is designed to bind to the fusion protein on the surface of the RSV virus. [12] [13]