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Janus particles are special types of nanoparticles or microparticles whose surfaces have two or more distinct physical properties. [1] [2] This unique surface of Janus particles allows two different types of chemistry to occur on the same particle. The simplest case of a Janus particle is achieved by dividing the particle into two distinct ...
Janus, also known by its name ZTF J203349.8+322901.1, is a transitioning white dwarf located more than 1,300 light-years (400 pc) away [3] in the constellation Cygnus, discovered in 2019 by the Zwicky Transient Facility (ZTF), located at the Palomar Observatory, while looking for periodically variable white dwarfs. [2] Subsequent observations using the Low-Resolution Imaging Spectrometer (LRIS ...
Janus is the ancient Roman god of beginnings, endings, transitions, and duality. Learn more about his symbols, myths, and cults on Wikipedia.
A Janus kinase inhibitor, also known as JAK inhibitor or jakinib, [1] is a type of immune modulating medication, which inhibits the activity of one or more of the Janus kinase family of enzymes ( JAK1, JAK2, JAK3, TYK2 ), thereby interfering with the JAK-STAT signaling pathway in lymphocytes . JAK inhibitors are used in the treatment of some ...
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Baricitinib is a Janus kinase (JAK) inhibitor that reversibly inhibits Janus kinase 1 with a half maximal inhibitory concentration (IC 50) of 5.9 nM and Janus kinase 2 with an IC 50 of 5.7 nM. Tyrosine kinase 2, which belongs to the same enzyme family, is affected less (IC 50 = 53 nM), and Janus kinase 3 far less (IC 50 > 400 nM).
The United States Pharmacopeia ( USP) is a pharmacopeia (compendium of drug information) for the United States published annually by the over 200-year old United States Pharmacopeial Convention (usually also called the USP), a nonprofit organization that owns the trademark and also owns the copyright on the pharmacopeia itself.
A Janus molecule (or Janus-faced molecule) is a molecule which can represent both beneficial and toxic effects. The term Janus-faced molecule is derived from the ancient Roman god, Janus.