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As with Adobe Acrobat, Nitro PDF Pro's reader is free; but unlike Adobe's free reader, Nitro's free reader allows PDF creation (via a virtual printer driver, or by specifying a filename in the reader's interface, or by drag-'n-drop of a file to Nitro PDF Reader's Windows desktop icon); Ghostscript not needed. PagePlus: Proprietary: No
Sumatra PDF is a free and open-source document viewer that supports many document formats including: Portable Document Format (PDF), Microsoft Compiled HTML Help (CHM), DjVu, EPUB, FictionBook (FB2), MOBI, PRC, Open XML Paper Specification (OpenXPS, OXPS, XPS), and Comic Book Archive file (CB7, CBR, CBT, CBZ).
Adobe Acrobat is one example of proprietary software that allows the user to annotate, highlight, and add notes to already created PDF files. One UNIX application available as free software (under the GNU General Public License) is PDFedit. The freeware Foxit Reader, available for Microsoft Windows, macOS and Linux, allows annotating documents.
Open Bioinformatics Foundation. BioPHP. PHP language toolkit with classes for DNA and protein sequence analysis, alignment, database parsing, and other bioinformatics tools. Cross-platform. GPL v2. Open Bioinformatics Foundation. Biopython. Python language toolkit. Cross-platform.
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