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(ADP-ribosyl)hydrolase 3 (ARH3) is an enzyme that in humans is encoded by the ADPRHL2 gene (also called ADPRS). This enzyme reverses the proteins’ post-translational addition of ADP-ribose to serine residues as part of the DNA damage response The enzyme is also known to cleave poly(ADP-ribose) polymers, 1''-O-acetyl-ADP-ribose and alpha-NAD +
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In enzymology, an ADP-ribosyl- [dinitrogen reductase] hydrolase ( EC 3.2.2.24) is an enzyme that catalyzes the chemical reaction. Hence, this enzyme has one substrate, [ [ADP-D-ribosyl- [dinitrogen reductase]]], and two products, ADP-D-ribose and dinitrogen reductase . This enzyme belongs to the family of hydrolases, specifically those ...
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Poly(ADP-ribose) polymerase family member 14 is a protein that, in humans, is encoded by the PARP14 gene.. Function. Poly(ADP-ribosyl)ation is an immediate DNA damage-dependent post-translational modification of histones and other nuclear proteins that contributes to the survival of injured proliferating cells.
n/a Ensembl ENSG00000169100 n/a UniProt P12236 Q6I9V5 n/a RefSeq (mRNA) NM_001636 n/a RefSeq (protein) NP_001627 NP_001627.2 n/a Location (UCSC) Chr X: 1.39 – 1.39 Mb n/a PubMed search n/a Wikidata View/Edit Human ADP/ATP translocase 3, also known as solute carrier family 25 member 6, is a protein that in humans is encoded by the SLC25A6 gene. Identical copies of this gene reside on the ...
In enzymology, an ADP-specific glucokinase (EC 2.7.1.147) also known as ADP-dependent glucokinase is an enzyme that catalyzes the chemical reaction. ADP + D-glucose AMP + D-glucose 6-phosphate. Thus, the two substrates of this enzyme are ADP and D-glucose, whereas its two products are AMP and D-glucose 6-phosphate.
The molecular target of the active metabolite of ADP receptor inhibitors is the P2Y 12 receptor. P2Y 12 receptor is a G-coupled receptor and is activated by adenosine diphosphate. ADP binds to the P2Y 12 receptor that leads to inhibition of adenyl cyclase and thereby decreases the intracellular