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James Parkinson. Parkinson's disease (PD), or simply Parkinson's, is a neurodegenerative disease of mainly the central nervous system that affects both the motor and non-motor systems of the body. The symptoms usually emerge slowly, and, as the disease progresses, non-motor symptoms become more common. Usual symptoms include tremors, slowness ...
Parkinson's Disease (journal) Parkinson's Disease. (journal) Parkinson's Disease is an open access medical journal covering Parkinson's disease. It was established in 2009 and is published by Hindawi Publishing Corporation. According to the Journal Citation Reports, the journal has a 2016 impact factor of 1.702. [1]
The unified Parkinson's disease rating scale (UPDRS) is used to follow the longitudinal course of Parkinson's disease. The UPD rating scale is the most commonly used scale in the clinical study of Parkinson's disease. [1] The UPDRS is made up of these sections: [2] Part I: evaluation of mentation, behavior, and mood
Hoehn and Yahr scale. The Hoehn and Yahr scale is a commonly used system for describing how the symptoms of Parkinson's disease progress. It was originally published in 1967 in the journal Neurology by Margaret Hoehn and Melvin Yahr and included stages 1 through 5. [1] Since then, a modified Hoehn and Yahr scale was proposed with the addition ...
Since the MoCA assesses multiple cognitive domains, it can be a useful cognitive screening tool for several neurological diseases that affect younger populations, such as Parkinson's disease, [14] [15] [16] vascular cognitive impairment, [17] [18] Huntington's disease, [19] brain metastasis, sleep behaviour disorder, [20] primary brain tumors ...
Management of Parkinson's disease. In the management of Parkinson's disease, due to the chronic nature of Parkinson's disease (PD), a broad-based program is needed that includes patient and family education, support-group services, general wellness maintenance, exercise, and nutrition. At present, no cure for the disease is known, but ...
Parkinson's Disease causes constipation and gastric dysmotility that is severe enough to endanger comfort and even health. [26] A factor in this is the appearance of Lewy bodies and Lewy neurites even before these affect the functioning of the substantia nigra in the neurons in the enteric nervous system that control gut functions. [27]
The first cell-based therapy investigated for Parkinson's disease utilized the adrenal medulla. The adrenal medulla is the innermost part of the adrenal gland and contains neural crest derived chromaffin cells which secrete norepinephrine, epinephrine and to a far lesser extent dopamine into the blood. Autotransplantation of adrenal medullary ...
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