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Minichromosome maintenance. Pfam maps to the core ATP binding domain. The minichromosome maintenance protein complex ( MCM) is a DNA helicase essential for genomic DNA replication. Eukaryotic MCM consists of six gene products, Mcm2–7, which form a heterohexamer. [1] [2] As a critical protein for cell division, MCM is also the target of ...
Website. www .bankmandiri .co .id. Footnotes / references. [1] PT Bank Mandiri (Persero) Tbk or Bank Mandiri, headquartered in Jakarta, [2] is the largest bank in Indonesia in terms of assets, loans and deposits. [3] Total assets as of 2022, were 1.992 Trillion rupiah (around US$133 Billion). As of 2022, Bank Mandiri is the largest bank in ...
The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre-RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication-related proteins. This protein forms a complex with MCM4, 6, and 7, and has been shown to regulate the helicase activity of the ...
The hexameric protein complex formed by the MCM proteins is a key component of the pre-replication complex (pre-RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. The MCM complex consisting of this protein and MCM2, 4 and 6 proteins possesses DNA helicase activity, and ...
Cdh1 is one of the co- activator proteins of APC/c and therefore contributes to the regulation of protein degradation, by providing substrate specificity to the E3-ligase in a cell cycle regulated manner. [citation needed] Cdh1 can exist in several forms. It can be phosphorylated by CDKs, which inactivates it and it can be dephosphorylated by ...
The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre-RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. The MCM complex consisting of this protein and MCM2, 6 and 7 proteins possesses DNA helicase activity, and may ...
Origin recognition complex. In molecular biology, origin recognition complex ( ORC) is a multi-subunit DNA binding complex (6 subunits) that binds in all eukaryotes and archaea in an ATP -dependent manner to origins of replication. The subunits of this complex are encoded by the ORC1, ORC2, ORC3, ORC4, ORC5 and ORC6 genes.
The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre-RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein is a subunit of the protein complex that consists of MCM2-7.