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Adenosine diphosphate ribose (ADPR) is an ester molecule formed into chains by the enzyme poly ADP ribose polymerase. ADPR is created from cyclic ADP-ribose (cADPR) by the CD38 enzyme using nicotinamide adenine dinucleotide (NAD +) as a cofactor. ADPR binds to and activates the TRPM2 ion channel. ADPR is the most potent agonist of the TRPM2 ...
ADP-specific phosphofructokinase. In enzymology, an ADP-specific phosphofructokinase ( EC 2.7.1.146) is an enzyme that catalyzes the chemical reaction. Thus, the two substrates of this enzyme are ADP and D-fructose 6-phosphate, whereas its two products are AMP and D-fructose 1,6-bisphosphate . This enzyme belongs to the family of transferases ...
(ADP-ribosyl)hydrolase 3 (ARH3) is an enzyme that in humans is encoded by the ADPRHL2 gene (also called ADPRS). This enzyme reverses the proteins’ post-translational addition of ADP-ribose to serine residues as part of the DNA damage response The enzyme is also known to cleave poly(ADP-ribose) polymers, 1''-O-acetyl-ADP-ribose and alpha-NAD +
ADP-thymidine kinase. In enzymology, an ADP—thymidine kinase ( EC 2.7.1.118) is an enzyme that catalyzes the chemical reaction. Thus, the two substrates of this enzyme are ADP and thymidine, whereas its two products are AMP and thymidine 5'-phosphate . This enzyme belongs to the family of transferases, specifically those transferring ...
ADP deaminase. In enzymology, an ADP deaminase ( EC 3.5.4.7) is an enzyme that catalyzes the chemical reaction. Thus, the two substrates of this enzyme are ADP and H 2 O, whereas its two products are IDP and NH 3 . This enzyme belongs to the family of hydrolases, those acting on carbon-nitrogen bonds other than peptide bonds, specifically in ...
Find out how to identify and correct common sign-in issues like problems with your username and password, account locks, looping logins, and other account access errors. Account Management · Feb 21, 2024. Get answers to your AOL Mail, login, Desktop Gold, AOL app, password and subscription questions. Find the support options to contact ...
ADP/ATP translocase 2 is a protein that in humans is encoded by the SLC25A5 gene on the X chromosome. [5] This protein functions as an antiporter for ADP/ ATP exchange between the mitochondrial matrix and cytoplasm. [5] [6] [7] As a result, it plays a key role in maintaining mitochondrial membrane potential and inhibiting apoptosis and has been ...
ADP-ribosylation is the addition of one or more ADP-ribose moieties to a protein. [1] [2] It is a reversible post-translational modification that is involved in many cellular processes, including cell signaling, DNA repair, gene regulation and apoptosis. [3] [4] Improper ADP-ribosylation has been implicated in some forms of cancer. [5]
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