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Adenosine diphosphate ribose (ADPR) is an ester molecule formed into chains by the enzyme poly ADP ribose polymerase. ADPR is created from cyclic ADP-ribose (cADPR) by the CD38 enzyme using nicotinamide adenine dinucleotide (NAD +) as a cofactor. ADPR binds to and activates the TRPM2 ion channel. ADPR is the most potent agonist of the TRPM2 ...
Adenosine diphosphate ( ADP) receptor inhibitors are a drug class of antiplatelet agents, used in the treatment of acute coronary syndrome (ACS) or in preventive treatment for patients who are in risk of thromboembolism, myocardial infarction or a stroke. These drugs antagonize the P2Y 12 platelet receptors and therefore prevent the binding of ...
The plus sign ( +) and the minus sign ( −) are mathematical symbols used to denote positive and negative functions, respectively. In addition, + represents the operation of addition, which results in a sum, while − represents subtraction, resulting in a difference. [1] Their use has been extended to many other meanings, more or less analogous.
View/Edit Mouse. In enzymology, an ADP-specific glucokinase ( EC 2.7.1.147) also known as ADP-dependent glucokinase is an enzyme that catalyzes the chemical reaction. ADP + D-glucose AMP + D-glucose 6-phosphate. Thus, the two substrates of this enzyme are ADP and D-glucose, whereas its two products are AMP and D-glucose 6-phosphate .
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