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  2. Parkinson's disease - Wikipedia

    en.wikipedia.org/wiki/Parkinson's_disease

    Parkinson's disease ( PD ), or simply Parkinson's, is a long-term neurodegenerative disease of mainly the central nervous system that affects both the motor system and non-motor systems. The symptoms usually emerge slowly, and as the disease progresses, non-motor symptoms become more common. Usual symptoms are tremor, slowness of movement ...

  3. History of Parkinson's disease - Wikipedia

    en.wikipedia.org/wiki/History_of_Parkinson's_disease

    The history of Parkinson's disease expands from 1817, when British apothecary James Parkinson published An Essay on the Shaking Palsy, to modern times. Before Parkinson's descriptions, others had already described features of the disease that would bear his name, while the 20th century greatly improved knowledge of the disease and its ...

  4. Causes of Parkinson's disease - Wikipedia

    en.wikipedia.org/wiki/Causes_of_Parkinson's_disease

    Parkinson's disease (PD) is a complicated neurodegenerative disease that progresses over time and is marked by bradykinesia, tremor, and stiffness. As the condition worsens, some patients may also experience postural instability. [1] Parkinson's disease (PD) is primarily caused by the gradual degeneration of dopaminergic neurons in the region ...

  5. Management of Parkinson's disease - Wikipedia

    en.wikipedia.org/wiki/Management_of_Parkinson's...

    Management of Parkinson's disease. In the management of Parkinson's disease, due to the chronic nature of Parkinson's disease (PD), a broad-based program is needed that includes patient and family education, support-group services, general wellness maintenance, exercise, and nutrition. At present, no cure for the disease is known, but ...

  6. Parkinson-plus syndrome - Wikipedia

    en.wikipedia.org/wiki/Parkinson-plus_syndrome

    Parkinson-plus syndromes ( PPS) are a group of neurodegenerative [1] diseases featuring the classical features of Parkinson's disease ( tremor, rigidity, akinesia / bradykinesia, and postural instability) with additional features that distinguish them from simple idiopathic Parkinson's disease (PD). Parkinson-plus syndromes are either inherited ...

  7. Animal models of Parkinson's disease - Wikipedia

    en.wikipedia.org/wiki/Animal_Models_of_Parkinson...

    Parkinson's disease is a neurodegenerative disorder, characterized by the loss of dopaminergic neurons in the substantia nigra pars compacta (SNpc). The loss of the dopamine neurons in the brain, results in motor dysfunction, ultimately causing the four cardinal symptoms of PD: tremor, rigidity, postural instability, and bradykinesia. [1]

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