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  2. Inhibitory postsynaptic potential - Wikipedia

    en.wikipedia.org/wiki/Inhibitory_postsynaptic...

    An inhibitory postsynaptic potential (IPSP) is a kind of synaptic potential that makes a postsynaptic neuron less likely to generate an action potential. [1] The opposite of an inhibitory postsynaptic potential is an excitatory postsynaptic potential (EPSP), which is a synaptic potential that makes a postsynaptic neuron more likely to generate ...

  3. Chemical synapse - Wikipedia

    en.wikipedia.org/wiki/Chemical_synapse

    Chemical synapses allow neurons to form circuits within the central nervous system. They are crucial to the biological computations that underlie perception and thought. They allow the nervous system to connect to and control other systems of the body. At a chemical synapse, one neuron releases neurotransmitter molecules into a small space (the ...

  4. Excitatory postsynaptic potential - Wikipedia

    en.wikipedia.org/wiki/Excitatory_postsynaptic...

    The summation of these three EPSPs generates an action potential. In neuroscience, an excitatory postsynaptic potential (EPSP) is a postsynaptic potential that makes the postsynaptic neuron more likely to fire an action potential. This temporary depolarization of postsynaptic membrane potential, caused by the flow of positively charged ions ...

  5. Synaptic potential - Wikipedia

    en.wikipedia.org/wiki/Synaptic_potential

    Synaptic potential refers to the potential difference across the postsynaptic membrane that results from the action of neurotransmitters at a neuronal synapse. [1] In other words, it is the “incoming” signal that a neuron receives. There are two forms of synaptic potential: excitatory and inhibitory.

  6. Postsynaptic potential - Wikipedia

    en.wikipedia.org/wiki/Postsynaptic_potential

    Postsynaptic potential. Postsynaptic potentials are changes in the membrane potential of the postsynaptic terminal of a chemical synapse. Postsynaptic potentials are graded potentials, and should not be confused with action potentials although their function is to initiate or inhibit action potentials. They are caused by the presynaptic neuron ...

  7. Ligand-gated ion channel - Wikipedia

    en.wikipedia.org/wiki/Ligand-gated_ion_channel

    Ligand-gated ion channels (LICs, LGIC), also commonly referred to as ionotropic receptors, are a group of transmembrane ion-channel proteins which open to allow ions such as Na +, K +, Ca 2+, and/or Cl − to pass through the membrane in response to the binding of a chemical messenger (i.e. a ligand), such as a neurotransmitter. [1][2][3] When ...

  8. Summation (neurophysiology) - Wikipedia

    en.wikipedia.org/wiki/Summation_(neurophysiology)

    Summation (neurophysiology) Basic ways that neurons can interact with each other when converting input to output. Summation, which includes both spatial summation and temporal summation, is the process that determines whether or not an action potential will be generated by the combined effects of excitatory and inhibitory signals, both from ...

  9. GABAB receptor - Wikipedia

    en.wikipedia.org/wiki/GABAB_receptor

    GABAB receptors (GABA B R) are G-protein coupled receptors for gamma-aminobutyric acid (GABA), therefore making them metabotropic receptors, that are linked via G-proteins to potassium channels. [1] The changing potassium concentrations hyperpolarize the cell at the end of an action potential. The reversal potential of the GABA B -mediated IPSP ...