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Wikipedia is the largest and most-read reference work in history, [3] [4] and is consistently ranked among the ten most visited websites; as of April 2024, it was ranked fourth by Semrush, [5] and seventh by Similarweb. [6]
Akt/PKB signaling pathway. The Akt signaling pathway or PI3K-Akt signaling pathway is a signal transduction pathway that promotes survival and growth in response to extracellular signals. Key proteins involved are PI3K ( phosphatidylinositol 3-kinase) and Akt ( protein kinase B ). Initial stimulation by one of the growth factors causes ...
t. e. The history of the Internet has its origin in the efforts of scientists and engineers to build and interconnect computer networks. The Internet Protocol Suite, the set of rules used to communicate between networks and devices on the Internet, arose from research and development in the United States and involved international collaboration ...
Crystal structure of Akt-2-inhibitor complexes. [2] Protein kinase B ( PKB ), also known as Akt, is the collective name of a set of three serine/threonine-specific protein kinases that play key roles in multiple cellular processes such as glucose metabolism, apoptosis, cell proliferation, transcription, and cell migration .
Sikhism ( / ˈsɪkɪzəm / SIK-iz-əm ), also known as Sikhi ( Punjabi: ਸਿੱਖੀ Sikkhī, [ˈsɪk.kʰiː] ⓘ, from ਸਿੱਖ, Sikh, 'disciple / learner'), [i] is an Indian religion [9] and philosophy [10] in particular for the Sikh ethnoreligious group that originated in the Punjab region of India [ii] around the end of the 15th ...
2-letter codes used by the United States Coast Guard (bold red text shows differences between ANSI and USCG) Abbreviations: GPO. Older variable-length official US Government Printing Office abbreviations. AP. Abbreviations from the AP Stylebook (bold red text shows differences between GPO and AP) Name and status of region. ISO.
according to International Monetary Fund estimates [n 1] [1] Countries by nominal GDP in 2019 [n 2] > $20 trillion. $10–20 trillion. $5–10 trillion. $1–5 trillion. $750 billion – $1 trillion. $500–750 billion. $250–500 billion.
Activating transcription factor. Activating transcription factor, ATF, is a group of bZIP transcription factors, which act as homodimers or heterodimers with a range of other bZIP factors. [1] First, they have been described as members of the CREB/ATF family, [2] whereas it turned out later that some of them might be more similar to AP-1 -like ...