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  2. Reticular formation - Wikipedia

    en.wikipedia.org/wiki/Reticular_formation

    The reticular formation is a set of interconnected nuclei in the brainstem that spans from the lower end of the medulla oblongata to the upper end of the midbrain. [2] The neurons of the reticular formation make up a complex set of neural networks in the core of the brainstem. [3] It is not anatomically well defined, because it includes neurons ...

  3. Neuroscience of sleep - Wikipedia

    en.wikipedia.org/wiki/Neuroscience_of_sleep

    The ascending reticular activating system consists of a set of neural subsystems that project from various thalamic nuclei and a number of dopaminergic, noradrenergic, serotonergic, histaminergic, cholinergic, and glutamatergic brain nuclei.

  4. Locus coeruleus - Wikipedia

    en.wikipedia.org/wiki/Locus_coeruleus

    It is a part of the reticular activating system. The locus coeruleus, which in Latin means "blue spot", is the principal site for brain synthesis of norepinephrine (noradrenaline). The locus coeruleus and the areas of the body affected by the norepinephrine it produces are described collectively as the locus coeruleus-noradrenergic system or LC ...

  5. Giuseppe Moruzzi - Wikipedia

    en.wikipedia.org/wiki/Giuseppe_Moruzzi

    Giuseppe Moruzzi (July 30, 1910 – March 11, 1986) was an Italian neurophysiologist. He was one of three scientists who connected wakefulness to a series of brain structures known as the reticular activating system, and his work reframed sleep as an active process in the brain rather than a passive one. He received the Karl Spencer Lashley ...

  6. Pedunculopontine nucleus - Wikipedia

    en.wikipedia.org/wiki/Pedunculopontine_nucleus

    The pedunculopontine nucleus (PPN) or pedunculopontine tegmental nucleus (PPT or PPTg) is a collection of neurons located in the upper pons in the brainstem. [1][2] It is involved in voluntary movements, [3] arousal, and provides sensory feedback to the cerebral cortex and one of the main components of the reticular activating system. [4][5] It ...

  7. Donald B. Lindsley - Wikipedia

    en.wikipedia.org/wiki/Donald_B._Lindsley

    Donald Benjamin Lindsley (December 23, 1907 – June 19, 2003) was an American physiological psychologist most known as a pioneer in the field of brain function study. . Considered by his colleagues to have been worthy of winning the Nobel Prize in Physiology for discovering the reticular activating system along with Horace Winchell (Tid) Magoun and Giuseppe Moruzzi, Lindsley was instrumental ...

  8. Activation-synthesis hypothesis - Wikipedia

    en.wikipedia.org/wiki/Activation-synthesis...

    Activation-synthesis hypothesis. The activation-synthesis hypothesis, proposed by Harvard University psychiatrists John Allan Hobson and Robert McCarley, is a neurobiological theory of dreams first published in the American Journal of Psychiatry in December 1977. The differences in neuronal activity of the brainstem during waking and REM sleep ...

  9. Arousal - Wikipedia

    en.wikipedia.org/wiki/Arousal

    Arousal is the physiological and psychological state of being awoken or of sense organs stimulated to a point of perception. It involves activation of the ascending reticular activating system (ARAS) in the brain, which mediates wakefulness, the autonomic nervous system, and the endocrine system, leading to increased heart rate and blood pressure and a condition of sensory alertness, desire ...