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Human brain in the coronal orientation. Amygdalae are shown in dark red. The amygdala (/ ə ˈ m ɪ ɡ d ə l ə /; pl.: amygdalae / ə ˈ m ɪ ɡ d ə l i,-l aɪ / or amygdalas; also corpus amygdaloideum; Latin from Greek, ἀμυγδαλή, amygdalē, 'almond', 'tonsil' [1]) is a paired nuclear complex present in the cerebral hemispheres of vertebrates.
The posterior pituitary (or neurohypophysis) is a lobe of the gland that is functionally connected to the hypothalamus by the median eminence via a small tube called the pituitary stalk (also called the infundibular stalk or the infundibulum).
The dura mater (Latin: tough mother), [6] [a] is a thick, durable membrane, closest to the skull and vertebrae.The dura mater, the outermost part, is a loosely arranged, fibroelastic layer of cells, characterized by multiple interdigitating cell processes, no extracellular collagen, [citation needed] and significant extracellular spaces.
The neocortex, also called the neopallium, isocortex, or the six-layered cortex, is a set of layers of the mammalian cerebral cortex involved in higher-order brain functions such as sensory perception, cognition, generation of motor commands, [1] spatial reasoning and language. [2]
In humans, it contains two main interlocking parts: the hippocampus proper (also called Ammon's horn), and the dentate gyrus. [6] [7] In Alzheimer's disease (and other forms of dementia), the hippocampus is one of the first regions of the brain to suffer damage; [8] short-term memory loss and disorientation are included
The Nodal signaling pathway is a signal transduction pathway important in regional and cellular differentiation during embryonic development. [1]The Nodal family of proteins, a subset of the transforming growth factor beta (TGFβ) superfamily, is responsible for mesoendoderm induction, patterning of the nervous system, and determination of dorsal- ventral axis in vertebrate embryos.
There are three activins: Activin A, Activin B and Activin AB. Activins are involved in embryogenesis and osteogenesis. They also regulate many hormones including pituitary, gonadal and hypothalamic hormones as well as insulin. They are also nerve cell survival factors. The BMPs bind to the bone morphogenetic protein receptor type-2 (BMPR2).
The striatum (pl.: striata) or corpus striatum [5] is a cluster of interconnected nuclei that make up the largest structure of the subcortical basal ganglia. [6] The striatum is a critical component of the motor and reward systems; receives glutamatergic and dopaminergic inputs from different sources; and serves as the primary input to the rest of the basal ganglia.