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Adenosine diphosphate ribose (ADPR) is an ester molecule formed into chains by the enzyme poly ADP ribose polymerase. ADPR is created from cyclic ADP-ribose (cADPR) by the CD38 enzyme using nicotinamide adenine dinucleotide (NAD +) as a cofactor. ADPR binds to and activates the TRPM2 ion channel. ADPR is the most potent agonist of the TRPM2 ...
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Paychex, Inc., headquartered in Rochester, New York, is a provider of human resources, payroll, and employee benefits outsourcing services for small- to medium-sized businesses. [1] The company has more than 100 offices serving approximately 740,000 payroll clients in the U.S. and Europe. [1] Paychex is ranked 681st on the Fortune 500 list of ...
Number of employees. 200 (2009) Website. www .theaccessgroup .com /en-au /products /micropay. Access MicrOpay is a supplier of integrated payroll and Human Capital Management people management software [1] and services to Australian and New Zealand businesses. The company is a wholly owned subsidiary of The Access Group .
ADP-ribosylation is the addition of one or more ADP-ribose moieties to a protein. [1] [2] It is a reversible post-translational modification that is involved in many cellular processes, including cell signaling, DNA repair, gene regulation and apoptosis. [3] [4] Improper ADP-ribosylation has been implicated in some forms of cancer. [5]
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