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The spike protein is very large, often 1200 to 1400 amino acid residues long; [8] it is 1273 residues in SARS-CoV-2. [5] It is a single-pass transmembrane protein with a short C-terminal tail on the interior of the virus, a transmembrane helix, and a large N-terminal ectodomain exposed on the virus exterior. [5] [7]
COVID-19 pandemic by location [1] ^ Countries which do not report data for a column are not included in that column's world total. ^ Data on member states of the European Union are individually listed, but are also summed here for convenience. They are not double-counted in world totals. ^ Does not include special administrative regions ( Hong ...
This article documents the chronology and epidemiology of SARS-CoV-2 in 2019, the virus that causes coronavirus disease 2019 ( COVID-19) and is responsible for the COVID-19 pandemic. The first human cases of COVID-19 known to have been identified were in Wuhan, Hubei, China, in December 2019. It marked the beginning of the 2019–2020 COVID-19 ...
A second wave, with a new variant that originated in the UK becoming dominant, began in the autumn and peaked in mid-January 2021, and was deadlier than the first. The UK started a COVID-19 vaccination programme in early December 2020. Generalised restrictions were gradually lifted and were mostly ended by August 2021.
As of 2023, the COVID-19 pandemic is an ongoing global pandemic of coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS CoV‑2). Its impact has been broad, affecting general society, the global economy, culture, ecology, politics, and other areas.
In January 2020, the World Health Organization (WHO) tentatively named it "2019-nCoV", short for "2019 Novel Coronavirus", or "2019 Novel Coronavirus Acute Respiratory Disease". This naming was based on the organization's 2015 guidelines for naming novel viruses and diseases, avoiding the use of geographic locations (such as Wuhan ), in part to ...
The COVID-19 pandemic in Nigeria was a part of the worldwide pandemic of coronavirus disease 2019 ( COVID-19) caused by severe acute respiratory syndrome coronavirus 2 ( SARS-CoV-2 ). The first confirmed case in Nigeria was announced on 27 February 2020, when an Italian national in Lagos tested positive for the virus.
The COVID-19 pandemic in Canada is part of the ongoing worldwide pandemic of coronavirus disease 2019 . It is caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Most cases over the course of the pandemic have been in Ontario, Quebec, British Columbia and Alberta. Confirmed cases have been reported in all of Canada's ...