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  2. Parkinson's disease - Wikipedia

    en.wikipedia.org/wiki/Parkinson's_disease

    Parkinson's disease ( PD ), or simply Parkinson's, is a long-term neurodegenerative disease of mainly the central nervous system that affects both the motor system and non-motor systems. The symptoms usually emerge slowly, and as the disease progresses, non-motor symptoms become more common. Usual symptoms are tremor, slowness of movement ...

  3. Trichloroethylene - Wikipedia

    en.wikipedia.org/wiki/Trichloroethylene

    A history of long-term exposure to high concentrations of trichloroethylene is a suspected environmental risk of Parkinson's disease. Metabolism. Trichloroethylene is metabolised to trichloroepoxyethane (TCE oxide) which rapidly isomerises to trichloroacetaldehyde (chloral). Chloral hydrates to chloral hydrate in the body.

  4. Causes of Parkinson's disease - Wikipedia

    en.wikipedia.org/wiki/Causes_of_Parkinson's_disease

    Parkinson's disease (PD) is a complicated neurodegenerative disease that progresses over time and is marked by bradykinesia, tremor, and stiffness. As the condition worsens, some patients may also experience postural instability. [1] Parkinson's disease (PD) is primarily caused by the gradual degeneration of dopaminergic neurons in the region ...

  5. Glenn Tipton - Wikipedia

    en.wikipedia.org/wiki/Glenn_Tipton

    Glenn Raymond Tipton (born 25 October 1947) is an English guitarist. Often noted for his complex playing style and classically influenced solos, he is best known as one of the lead guitarists for the heavy metal band Judas Priest. He is the second longest-serving member of the band, after bassist and co-founder Ian Hill.

  6. Manganism - Wikipedia

    en.wikipedia.org/wiki/Manganism

    Manganism. - biochemical blood test: determination of the activity of ALT, ACT, LDH, creatine phosphokinase (CPK); - indicators of protein metabolism, - concentrations of thyroid hormones.Instrumental research. EEG, CT, MRI, global EMG, ENMG data are evaluated. Manganism or manganese poisoning is a toxic condition resulting from chronic ...

  7. Animal models of Parkinson's disease - Wikipedia

    en.wikipedia.org/wiki/Animal_Models_of_Parkinson...

    Parkinson's disease is a neurodegenerative disorder, characterized by the loss of dopaminergic neurons in the substantia nigra pars compacta (SNpc). The loss of the dopamine neurons in the brain, results in motor dysfunction, ultimately causing the four cardinal symptoms of PD: tremor, rigidity, postural instability, and bradykinesia. [1]

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