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Akt/PKB signaling pathway. The Akt signaling pathway or PI3K-Akt signaling pathway is a signal transduction pathway that promotes survival and growth in response to extracellular signals. Key proteins involved are PI3K ( phosphatidylinositol 3-kinase) and Akt ( protein kinase B ). Initial stimulation by one of the growth factors causes ...
Crystal structure of Akt-2-inhibitor complexes. [2] Protein kinase B ( PKB ), also known as Akt, is the collective name of a set of three serine/threonine-specific protein kinases that play key roles in multiple cellular processes such as glucose metabolism, apoptosis, cell proliferation, transcription, and cell migration .
New Kids on the Block (also initialized as NKOTB) is an American boy band from Dorchester, Massachusetts. The band consists of brothers Jonathan and Jordan Knight, Joey McIntyre, Donnie Wahlberg, and Danny Wood. New Kids on the Block enjoyed success in the late 1980s and early 1990s and have sold more than 80 million records worldwide, and are ...
System information modelling ( SIM) is the process of modelling complex connected systems. System information models are digital representations of connected systems, such as electrical instrumentation and control, power, and communication systems. The objects modelled in a SIM have a 1:1 relationship with the objects in the physical system.
Printed circuit board of a DVD player. Part of a 1984 Sinclair ZX Spectrum computer board, a printed circuit board, showing the conductive traces, the through-hole paths to the other surface, and some electronic components mounted using through-hole mounting. A printed circuit board ( PCB ), also called printed wiring board ( PWB ), is a medium ...
AKT1. RAC (Rho family)-alpha serine/threonine-protein kinase is an enzyme that in humans is encoded by the AKT1 gene. This enzyme belongs to the AKT subfamily of serine/threonine kinases that contain SH2 (Src homology 2-like) protein domains. [5] It is commonly referred to as PKB, or by both names as "Akt/PKB".
Function. This gene encodes a cytoplasmic protein tyrosine kinase that is involved in calcium-induced regulation of ion channels and activation of the MAP kinase signaling pathway. The encoded protein may represent an important signaling intermediate between neuropeptide-activated receptors or neurotransmitters that increase calcium flux and ...
Roger Keith " Syd " Barrett (6 January 1946 – 7 July 2006) was an English singer, guitarist and songwriter who co-founded the rock band Pink Floyd in 1965. Barrett was the band's original frontman and primary songwriter, known for his whimsical style of psychedelia, [1] English-accented singing, and stream-of-consciousness writing style. [4]