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Protein kinase B (PKB), also known as Akt, is the collective name of a set of three serine/threonine-specific protein kinases that play key roles in multiple cellular processes such as glucose metabolism, apoptosis, cell proliferation, transcription, and cell migration.
Akt/PKB signaling pathway. The Akt signaling pathway or PI3K-Akt signaling pathway is a signal transduction pathway that promotes survival and growth in response to extracellular signals. Key proteins involved are PI3K (phosphatidylinositol 3-kinase) and Akt (protein kinase B). Initial stimulation by one of the growth factors causes activation ...
AKT1. RAC (Rho family)-alpha serine/threonine-protein kinase is an enzyme that in humans is encoded by the AKT1 gene. This enzyme belongs to the AKT subfamily of serine/threonine kinases that contain SH2 (Src homology 2-like) protein domains. [5] It is commonly referred to as PKB, or by both names as "Akt/PKB".
Public-key cryptography, or asymmetric cryptography, is the field of cryptographic systems that use pairs of related keys. Each key pair consists of a public key and a corresponding private key. [1][2] Key pairs are generated with cryptographic algorithms based on mathematical problems termed one-way functions.
National Awakening Party. The National Awakening Party (Indonesian: Partai Kebangkitan Bangsa; lit. 'Party of the Nation's Awakening'), frequently abbreviated to PKB, is an Islam -based [5][6] political party in Indonesia. It is also the party of the current Vice President of Indonesia, Ma'ruf Amin, who was elected to its Syura Council.
Hexahydro-1,3,5-triazine. In chemistry, hexahydro-1,3,5-triazine is a class of heterocyclic compounds with the formula (CH 2 NR) 3. Known as aldehyde ammonias, these compounds characteristically crystallize with water. They are reduced derivatives of 1,3,5- triazine, which have the formula (CHN) 3, a family of aromatic heterocycles.
A transcription factor is a protein that binds to specific DNA sequences (enhancer or promoter), either alone or with other proteins in a complex, to control the rate of transcription of genetic information from DNA to messenger RNA by promoting (serving as an activator) or blocking (serving as a repressor) the recruitment of RNA polymerase. [3 ...
The PI3K/AKT/mTOR pathway is an intracellular signaling pathway important in regulating the cell cycle. Therefore, it is directly related to cellular quiescence, proliferation, cancer, and longevity. PI3K activation phosphorylates and activates AKT, localizing it in the plasma membrane. [1] AKT can have a number of downstream effects such as ...