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Xeroderma pigmentosum ( XP) is a genetic disorder in which there is a decreased ability to repair DNA damage such as that caused by ultraviolet (UV) light. [1] Symptoms may include a severe sunburn after only a few minutes in the sun, freckling in sun-exposed areas, dry skin and changes in skin pigmentation. [1]
Nucleotide excision repair (NER) is a particularly important excision mechanism that removes DNA damage induced by ultraviolet light (UV). UV DNA damage results in bulky DNA adducts — these adducts are mostly thymine dimers and 6,4-photoproducts. Recognition of the damage leads to removal of a short single-stranded DNA segment that contains ...
22590 Ensembl ENSG00000136936 ENSMUSG00000028329 UniProt P23025 Q64267 RefSeq (mRNA) NM_000380 NM_011728 RefSeq (protein) NP_000371 NP_001341904 NP_035858 Location (UCSC) n/a Chr 4: 46.16 – 46.2 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse DNA repair protein complementing XP-A cells is a protein that in humans is encoded by the XPA gene. Function Nucleotide excision repair (NER ...
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Windows XP is a major release of Microsoft's Windows NT operating system. It was released to manufacturing on August 24, 2001, and later to retail on October 25, 2001. It is a direct upgrade to its predecessors, Windows 2000 for high-end and business users and Windows Me for home users, and is available for any devices running Windows NT 4.0, Windows 98, Windows 2000, or Windows Me that meet ...
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