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Tramadol, sold under the brand name Ultram among others, [1] is an opioid pain medication and a serotonin–norepinephrine reuptake inhibitor (SNRI) used to treat moderately severe pain. [3] [13] When taken by mouth in an immediate-release formulation, the onset of pain relief usually begins within an hour. [3]
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Tramadol/paracetamol, also known as tramadol/acetaminophen and sold under the brand name Ultracet, is a fixed-dose combination medication used for the treatment of moderate to severe pain. [2] [3] It contains tramadol hydrochloride and paracetamol .
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Monoamine oxidase inhibitor. Monoamine oxidase inhibitors ( MAOIs) are a class of drugs that inhibit the activity of one or both monoamine oxidase enzymes: monoamine oxidase A (MAO-A) and monoamine oxidase B (MAO-B). They are best known as effective antidepressants, especially for treatment-resistant depression and atypical depression. [1]
v. t. e. In the United States, prescription monitoring programs ( PMPs) or prescription drug monitoring programs ( PDMPs) are state-run programs which collect and distribute data about the prescription and dispensation of federally controlled substances and, depending on state requirements, other potentially abusable prescription drugs.
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Tramadol and tapentadol carry additional risks associated with their dual effects as SNRIs and can cause serotonin syndrome and seizures. Despite these risks, there is evidence to suggest that these drugs have a lower risk of respiratory depression compared to morphine. See also. δ-opioid receptor; κ-opioid receptor; References