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Hereditary nonpolyposis colorectal cancer (HNPCC) is a hereditary predisposition to colon cancer.. HNPCC includes (and was once synonymous with) [1] Lynch syndrome, an autosomal dominant genetic condition that is associated with a high risk of colon cancer, endometrial cancer (second most common), ovary, stomach, small intestine, hepatobiliary tract, upper urinary tract, brain, and skin. [2]
MSI is a good marker for detecting Lynch syndrome and determining a prognosis for cancer treatments. In 1996, the National Cancer Institute (NCI) hosted an international workshop on Lynch Syndrome, which led to the development of the “Bethesda Guidelines” and loci for MSI testing.
The term MSI is defined in US federal statute under the Higher Education Act (HEA), and several federal agencies maintain a listing of eligible institutions that receive HEA funding designated for MSIs, such as the U.S. Department of Education and the National Science Foundation.
The member states of the United Nations comprise 193 sovereign states. The United Nations (UN) is the world's largest intergovernmental organization. All members have equal representation in the UN General Assembly. [3] The Charter of the United Nations defines the rules for admission of member states. Membership is open to all states which ...
The NAR were directed by former RAI child actor, Valerio Fioravanti, his brother Cristiano Fioravanti, Dario Pedretti, Francesca Mambro and Alessandro Alibrandi, who were previous militants of the Italian Social Movement (MSI). [6] Other important members included: Luigi Ciavardini, Gilberto Cavallini, Stefano Soderini, Franco Anselmi, Giorgio ...
Fini had been close to Almirante since 1977 when the MSI leader had Fini appointed chief of the MSI youth movement even though he had only finished seventh in the members vote. [23] Fini largely followed in Almirante's footsteps of attempting to shift Italy from a parliamentary to a fully presidential system.
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