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The Pfizer–BioNTech COVID-19 vaccine, sold under the brand name Comirnaty, [2] [32] is an mRNA-based COVID-19 vaccine developed by the German biotechnology company BioNTech. For its development, BioNTech collaborated with the American company Pfizer to carry out clinical trials, logistics, and manufacturing. [44] [45] It is authorized for use ...
Corbevax is a protein subunit COVID-19 vaccine developed by Texas Children's Hospital Center for Vaccine Development and Baylor College of Medicine in Houston, Texas and Dynavax technologies based in Emeryville, California.
More serious side effects are very rare. Before COVID-19 vaccines such as Moderna and Pfizer/BioNTech were authorized for use in the general population, they had to pass phase III studies involving tens of thousands of people. Any serious side effects that did not appear during that testing are likely to occur less often than ~1 in 10,000 cases.
A vaccine dose contains many ingredients (stabilizers, adjuvants, residual inactivating ingredients, residual cell culture materials, residual antibiotics and preservatives) very little of which is the active ingredient, the immunogen. A single dose may have merely nanograms of virus particles, or micrograms of bacterial polysaccharides. A ...
Severe side effects are defined as those that prevent daily activity. Efficacy. The COVID-19 mRNA vaccines from Moderna and Pfizer–BioNTech have efficacy rates of 90 to 95 percent [citation needed]. Prior mRNA, drug trials on pathogens other than COVID-19 were not effective and had to be abandoned in the early phases of trials.
CoronaVac, also known as the Sinovac COVID-19 vaccine, [3] is a whole inactivated virus COVID-19 vaccine developed by the Chinese company Sinovac Biotech. [4] [5] It was phase III clinically trialled in Brazil, [6] Chile, [7] Indonesia, [8] the Philippines, [9] and Turkey [10] and relies on traditional technology similar to other inactivated ...
It has been deployed in the Pfizer-BioNTech SARS-CoV-2 mRNA vaccine (0.05 mg per dose) that contains the active ingredient tozinameran. See also Pfizer–BioNTech COVID-19 vaccine nanoparticle ingredients. ALC-0315; 1,2-distearoyl-sn-glycero-3-phosphocholine; Cholesterol; Others. Polyethoxylated tallow amine; References
Volunteers receiving a second dose of the Pfizer-BioNTech vaccine remained more than 90% protected against symptomatic COVID-19.
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