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Xeroderma pigmentosum ( XP) is a genetic disorder in which there is a decreased ability to repair DNA damage such as that caused by ultraviolet (UV) light. [1] Symptoms may include a severe sunburn after only a few minutes in the sun, freckling in sun-exposed areas, dry skin and changes in skin pigmentation. [1]
22590 Ensembl ENSG00000136936 ENSMUSG00000028329 UniProt P23025 Q64267 RefSeq (mRNA) NM_000380 NM_011728 RefSeq (protein) NP_000371 NP_001341904 NP_035858 Location (UCSC) n/a Chr 4: 46.16 – 46.2 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse DNA repair protein complementing XP-A cells is a protein that in humans is encoded by the XPA gene. Function Nucleotide excision repair (NER ...
Nucleotide excision repair (NER) is a particularly important excision mechanism that removes DNA damage induced by ultraviolet light (UV). UV DNA damage results in bulky DNA adducts — these adducts are mostly thymine dimers and 6,4-photoproducts. Recognition of the damage leads to removal of a short single-stranded DNA segment that contains ...
Windows XP is a major release of Microsoft's Windows NT operating system. It was released to manufacturing on August 24, 2001, and later to retail on October 25, 2001. It is a direct upgrade to its predecessors, Windows 2000 for high-end and business users and Windows Me for home users, and is available for any devices running Windows NT 4.0, Windows 98, Windows 2000, or Windows Me that meet ...
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View/Edit Human. View/Edit Mouse. ERCC4 is a protein designated as DNA repair endonuclease XPF that in humans is encoded by the ERCC4 gene. Together with ERCC1, ERCC4 forms the ERCC1-XPF enzyme complex that participates in DNA repair and DNA recombination. [5] [6] The nuclease enzyme ERCC1-XPF cuts specific structures of DNA.
avg .com /avg-pctuneup. AVG TuneUp, previously called AVG PC Tuneup, and TuneUp Utilities, is a utility software suite for Microsoft Windows designed to help manage, maintain, optimize, configure, and troubleshoot a computer system. It was produced and developed by TuneUp Software GmbH. TuneUp Software was headquartered in Darmstadt, Germany ...
XPC (gene) Xeroderma pigmentosum, complementation group C, also known as XPC, is a protein which in humans is encoded by the XPC gene. XPC is involved in the recognition of bulky DNA adducts in nucleotide excision repair. [4] It is located on chromosome 3. [5]
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