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Frequency. <1 in 100,000 infants. [1] Autoimmune enteropathy is a rare autoimmune disorder characterized by weight loss from malabsorption, severe and protracted diarrhea, and autoimmune damage to the intestinal mucosa. [1] Autoimmune enteropathy typically occurs in infants and younger children however, adult cases have been reported in ...
Coordinates: 33°37′36″N 85°59′9″W. Anniston Chemical Activity was a U.S. Army chemical weapon storage site located in Alabama. The Army had stored approximately seven percent of the nation’s original chemical weapons stockpile at the Anniston Army Depot since the early 1960s. In August 2003, the Army began disposing of these weapons ...
Life expectancy is greatly reduced for people with Creutzfeldt–Jakob disease, with the average being less than 6 months. As of 1981, no one was known to have lived longer than 2.5 years after the onset of CJD symptoms. [ 65 ]
Rheumatology. Eosinophilia–myalgia syndrome is a rare, sometimes fatal neurological condition linked to the ingestion of the dietary supplement L-tryptophan. [1][2] The risk of developing EMS increases with larger doses of tryptophan and increasing age. [3] Some research suggests that certain genetic polymorphisms may be related to the ...
The first symptoms may begin as early as the first day of life or as late as adulthood. [4] Symptoms can range from mild to life-threatening. [1] Some forms can result in death if undiagnosed or left untreated. Methylmalonic acidemias are found with an equal frequency across ethnic boundaries. [5]
Glycine encephalopathy. Glycine encephalopathy is a rare autosomal recessive disorder of glycine metabolism. After phenylketonuria, glycine encephalopathy is the second most common disorder of amino acid metabolism. The disease is caused by defects in the glycine cleavage system, an enzyme responsible for glycine catabolism.
Amyloid light-chain (AL) amyloidosis, also known as primary amyloidosis, is the most common form of systemic amyloidosis. [1] The disease is caused when a person's antibody -producing cells do not function properly and produce abnormal protein fibers made of components of antibodies called light chains. These light chains come together to form ...
Chronic solvent-induced encephalopathy (CSE) is a condition induced by long-term exposure to organic solvents, often—but not always—in the workplace, that lead to a wide variety of persisting sensorimotor polyneuropathies and neurobehavioral deficits even after solvent exposure has been removed. [1][2][3] This syndrome can also be referred ...