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Channelrhodopsin-1 (ChR1) and Channelrhodopsin-2 (ChR2) from the model organism Chlamydomonas reinhardtii are the first discovered channelrhodopsins. Variants that are sensitive to different colors of light or selective for specific ions (ACRs, KCRs) have been cloned from other species of algae and protists .
Optogenetics. Optogenetics is a biological technique to control the activity of neurons or other cell types with light. This is achieved by expression of light-sensitive ion channels, pumps or enzymes specifically in the target cells. On the level of individual cells, light-activated enzymes and transcription factors allow precise control of ...
The Vanderbilt family is an American family who gained prominence during the Gilded Age. Their success began with the shipping and railroad empires of Cornelius Vanderbilt, and the family expanded into various other areas of industry and philanthropy. Cornelius Vanderbilt's descendants went on to build grand mansions on Fifth Avenue in New York ...
Anion-conducting channelrhodopsins are light-gated ion channels that open in response to light and let negatively charged ions (such as chloride) enter a cell. All channelrhodopsins use retinal as light-sensitive pigment, but they differ in their ion selectivity. Anion-conducting channelrhodopsins are used as tools to manipulate brain activity ...
Vanderbilt University (informally Vandy or VU) is a private research university in Nashville, Tennessee.Founded in 1873, it was named in honor of shipping and railroad magnate Cornelius Vanderbilt, who provided the school its initial $1 million endowment in the hopes that his gift and the greater work of the university would help to heal the sectional wounds inflicted by the American Civil War.
George Washington Vanderbilt II (November 14, 1862 – March 6, 1914) was an American art collector and member of the prominent Vanderbilt family, which amassed a huge fortune through steamboats, railroads, and various business enterprises. [1] He commissioned the construction of a 250-room mansion, the largest privately owned home in the ...
e. The Vanderbilt ADHD Diagnostic Rating Scale ( VADRS) is a psychological assessment tool for attention deficit hyperactivity disorder (ADHD) symptoms and their effects on behavior and academic performance in children ages 6–12. This measure was developed by Mark L Wolraich at the Oklahoma Health Sciences Center [1] and includes items ...
Cornelius Vanderbilt (May 27, 1794 – January 4, 1877), nicknamed "the Commodore", was an American business magnate who built his wealth in railroads and shipping. After working with his father's business, Vanderbilt worked his way into leadership positions in the inland water trade and invested in the rapidly growing railroad industry, effectively transforming the geography of the United States.