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Channelrhodopsin-1 (ChR1) and Channelrhodopsin-2 (ChR2) from the model organism Chlamydomonas reinhardtii are the first discovered channelrhodopsins. Variants that are sensitive to different colors of light or selective for specific ions (ACRs, KCRs) have been cloned from other species of algae and protists .
The Vanderbilt University Medical Center (VUMC) is a medical provider with multiple hospitals in Nashville, Tennessee, as well as clinics and facilities throughout Middle Tennessee. VUMC is an independent non-profit organization, but maintains academic affiliations with Vanderbilt University. As of 2023, the health system had more than 3 ...
Optogenetics. Optogenetics is a biological technique to control the activity of neurons or other cell types with light. This is achieved by expression of light-sensitive ion channels, pumps or enzymes specifically in the target cells. On the level of individual cells, light-activated enzymes and transcription factors allow precise control of ...
March 26, 2024 at 6:03 AM. A lawsuit against Vanderbilt University Medical Center over the release of medical records of some patients of its transgender health clinic will move forward albeit ...
Chromosome 2 is one of the twenty-three pairs of chromosomes in humans. People normally have two copies of this chromosome. Chromosome 2 is the second-largest human chromosome, spanning more than 242 million base pairs [4] and representing almost eight percent of the total DNA in human cells .
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GCaMP is a genetically encoded calcium indicator (GECI) initially developed in 2001 by Junichi Nakai. [1] It is a synthetic fusion of green fluorescent protein (GFP), calmodulin (CaM), and M13, a peptide sequence from myosin light-chain kinase. [2] When bound to Ca 2+, GCaMP fluoresces green with a peak excitation wavelength of 480 nm and a ...
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