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Adrenocorticotropic hormone ( ACTH; also adrenocorticotropin, corticotropin) is a polypeptide tropic hormone produced by and secreted by the anterior pituitary gland. [1] It is also used as a medication and diagnostic agent. ACTH is an important component of the hypothalamic-pituitary-adrenal axis and is often produced in response to biological ...
ACTH stimulation test. The ACTH test (also called the cosyntropin, tetracosactide, or Synacthen test) is a medical test usually requested and interpreted by endocrinologists to assess the functioning of the adrenal glands ' stress response by measuring the adrenal response to adrenocorticotropic hormone (ACTH; corticotropin) or another ...
A chemotherapy regimen is a regimen for chemotherapy, defining the drugs to be used, their dosage, the frequency and duration of treatments, and other considerations. In modern oncology, many regimens combine several chemotherapy drugs in combination chemotherapy. The majority of drugs used in cancer chemotherapy are cytostatic, many via ...
Determining the appropriate regimen to use depends on many factors; such as, the character of the tumor, lymph node status, and the age and health of the patient. [3] The following is a list of some of the commonly used adjuvant chemotherapy for breast cancer: CMF: cyclophosphamide, methotrexate, and 5- fluorouracil. [4]
Glucocorticoids. [2] Adrenocorticotropic hormone deficiency is a rare disorder characterized by secondary adrenal insufficiency with minimal or no cortisol production and normal pituitary hormone secretion apart from ACTH. [3] ACTH deficiency may be congenital or acquired, and its symptoms are clinically similar to those of glucocorticoid ...
Adrenocorticotropic hormone is used as a medication and as diagnostic agent in the ACTH stimulation test. [1] [2] : 316, 1165 [3] : 84, 271. The form that is purified from pig pituitary glands is known as corticotropin [1] [2] : 316 is a medication and naturally occurring polypeptide tropic hormone produced and secreted by the anterior ...
Adjuvant therapy. Adjuvant therapy, also known as adjunct therapy, adjuvant care, or augmentation therapy, is a therapy that is given in addition to the primary or initial therapy to maximize its effectiveness. The surgeries and complex treatment regimens used in cancer therapy have led the term to be used mainly to describe adjuvant cancer ...
ACTH receptor. The adrenocorticotropic hormone receptor or ACTH receptor also known as the melanocortin receptor 2 or MC2 receptor is a type of melanocortin receptor (type 2) which is specific for ACTH. [5] A G protein–coupled receptor located on the external cell plasma membrane, it is coupled to G αs and upregulates levels of cAMP by ...