The 46664 Foundation, named after the number former South African President Nelson Mandela wore while imprisoned for 27 tears, aims to raise awareness and to educate people about the global HIV/AIDS crisis. The campaign began in 2003, when Mandela realized that to reach the youth of the world he needed to engage the support of the people who most appeal to them. Mandela, supported by Dave Stewart of Eurythmics, Brian May and Roger Taylor of Queen, and Bono (natch), persuaded more than 30 of the world's top artists to come together to perform at a global awareness concert for HIV/AIDS in Cape Town.

Mandela will be 90 this year, and to celebrate, as well as to raise funds for 46664, there will be a global launch of limited-edition 46664 wrist bangles during the birthday celebrations in London on June 27. The goal is to create jobs as well as bring at least R1-billion (R=South African Rand, equal to $0.12587 on June 23) to the fight against HIV/Aids. Offered will be 90 platinum bangles (at the cost of R135 660 each), 90 24-carat gold bangles (R67 260), 466 18-carat gold bangles (R54 948) and 46,664 silver bangles (R1 995). The initiative will be a South African effort using metals from local suppliers, the skills of local craftsman and domestic suppliers from the tooling, machining and packaging industries. At least 60 percent of revenues from the sale of bangles will go to the 46664 HIV/Aids prevention campaign.

You can donate directly to 46664 here.

AIDS is officially 25 years old and sadly in many ways it's as strong and as deadly as ever. In certain parts of South Africa as much as 41% of the population is afflicted with AIDS, and worldwide 90% of the people who have it don't know it. Ignorance is one of the biggest hurdles in treating and controlling the spread of AIDS, and Keep a Child Alive is an organization focused on helping with both education, treatment, and prevention of this devastating disease -- not to mention support of the children left in its wake.

To date over 15 million children have lost one or both parents to the AIDS pandemic, and for just $1 a day you can buy the drugs needed to keep a child alive.

UNICEF is a well-known charitable organization that promotes the health and well-being of children with HIV and AIDS. And this season fashion house Moschino has collaborated with UNICEF and come up with a beautiful way to raise funds: The Love Clock.

It's a clear plexiglass "doll" with a bright red heart in the center where the clock hands are centered, and the design is the result of 70 Italian artists and designers gathering together in collaboration. The clock will go up for auction on December 18th at Sothebys and all proceeds will go to benefit UNICEF.

If you can't make the auction (or if you make it there but you lose the bidding) and you still want to support UNICEF you can do it any number of ways -- including through these darling seasonal cards.

The Associated Press reports that Bono announced a new program to fight HIV and AIDS in Africa. Products under the Red brand will divert some revenue to the Global Fund to Fight AIDS, Tuberculosis and Malaria. So far American Express, Converse, Gap and Giorgio Armani have jumped on the Red bandwagon. The red American Express card will launch in Britain next month. Some of the products will be produced in Africa with African materials. It is hoped that the new initiative will raise millions of dollars for the Global Fund.